Off-label use means prescribing an FDA-approved medication for a condition or in a way not listed on its official label, which is legal and often supported by evidence. Insurers sometimes deny off-label prescriptions as experimental, even when medical literature backs them. Citing compendia or peer-reviewed studies is a common way to appeal these denials.
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Disclaimer: This definition is provided for general educational purposes only and is not legal, medical, or insurance advice. Insurance rules, deadlines, and terminology vary by plan, state, and over time. Always check your own plan documents and confirm current details before acting.